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NU7441

CAT: 0498-bs-83029C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83029C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NU7441 is a potent (IC50 = 13 nM) and selective ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK) .1,2 It increased the toxicity of ionizing radiation and etoposide on SW620 human colon cancer lines via impeding of DNA double-strand break repair.3 NU7441 also increased the radio/chemosensitivity of various other cancer cell lines.3-6
Conjugation
Unconjugated
Buffer
Off-white to beige solid
Storage Conditions
-20°C

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TBI4810-25MGNU7441, DNA-PK inhibitor

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