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Fruquintinib

CAT: 0498-bs-83018C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83018C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Fruquintinib is a potent and highly selective inhibitor of VEGFR kinase (IC50’s: VEGFR1= 33 nM, VEGFR2 = 35 nM, VEGFR3 = 0.5 nM) .1 It potently inhibited VEGF/VEGFR signaling and cell proliferation in HUVECs and HLECs and prevented angiogenesis in vitro. Fruquintinib is currently is several clinical trials against metastatic colorectal cancer2 and nonsquamous non-small-cell lung cancer3.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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