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MOMIPP

CAT: 0498-bs-83012C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83012C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MOMIPP is an inducer of Methuosis, a novel form of nonapoptotic cell death.1 Methuosis is characterized by fusion of macropinocytotic vesiscles into progressively larger vacuoles resulting in a decrease in metabolic activity and rupture of the cell membrane.2 MOMIPP was able to effectively reduce the growth and viability of Temozolomide-resistant glioblastoma and doxorubicin-resistant breast cancer cells at low micromolar concentrations. MOMMIP has also been shown to disrupt vesicular trafficking at the lysosomal nexus resulting in impaired degradation of EGF and LDL receptors, defective processing of procathepsins and accumulation of autophagosomes.3
Conjugation
Unconjugated
Buffer
Orange solid
Storage Conditions
-20°C

Alternative Products

CatalogName
BA8774-1MOMIPP
HY-1154586-MOMIPP

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