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BO-264

CAT: 0498-bs-82989C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82989C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BO-264 is a potent (IC50 = 188 nM) inhibitor of transforming acidic coiled-coil 3 (TACC3), an important protein involved in microtubule stability and centrosome integrity.1 TACC3 is frequently upregulated in a broad range of cancers. BO-264 displayed significant anticancer activity in greater than 90% of cell lines in the NCI-60 human cancer cell line panel. Active in vivo in mice injected with JIMT-1 and EMT6 breast cancer cells as well as mouse colon cancer xenografts HCT-116 and CT-26.
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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BA2847-10BO-264
A22318-1BO-264 1mg
A22318-100BO-264 100mg
A22318-10BO-264 10mg
A22318-5BO-264 5mg
A22318-50BO-264 50mg
A22318-25BO-264 25mg
TBI4685-5MGBO-264, TACC3 inhibitor

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