Products for Research Use Only

R428

CAT: 0498-bs-82982C-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0498-bs-82982C-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
R428 (1037624-75-1) is a potent and selective inhibitor of AXL kinase (IC50 = 1.4nM) .1 R428 has been shown to overcome chemotherapy resistance to various agents in multiple cancer models.2-5 AXL has been shown to suppress myeloid cell activation and function – combined AXL inhibition with R428 and PD-1 blockade showed potent synergistic antitumor effects.6,7
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C