RIPA-56

• Background:

  RIPA-56 is a potent (IC50 = 13 nM, EC50 = 28nM for HT-29 cells) and selective inhibitor of Receptor-Interacting Protein 1 (RIP1) kinase with significant metabolic stability (t1/2 = 128min human liver microsomal stability assay) . RIPA-56 showed excellent kinase selectivity and did not inhibit IDO at 200 µM.

• Conjugation:

  Unconjugated

• Buffer:

  White solid

• Storage Conditions:

  -20°C