Rbin-1

• Background :

  Rbin-1 is potent (GI50 = 136 nM) and reversible inhibitor of eukaryotic ribosome assembly. The biochemical target of Rbin-1 is Midasin (Mdn1), an essential AAA+ protein. Blocking of Mdn1 by Rbin-1 inhibits the processing of pre-60S particles, important pre-ribosomal subunits produced in the nucleolus.

• Conjugation :

  Unconjugated

• Buffer :

  Pale yellow solid

• Storage Conditions :

  -20°C