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UNC1999

CAT: 0498-bs-82908C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82908C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
UNC1999 is an orally bioavailable, highly selective inhibitor of both wild-type and mutant EZH1 and EZH2 lysine methyltransferases (IC50’s = 45 nM and 2 nM respectively) .1 Inhibition of EZH2 with UNC1999 enhanced the efficacy of gefitinib in suppressing the proliferation of colon cancer cells
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

Alternative Products

CatalogName
MBS516367-01UNC1999
TBI4542-25MGUNC1999, Methyltransferase inhibitor
217350Ezh2/Ezh1 Inhibitor, UNC1999 (Enhancer of Zested Homolog 1 Inhibitor, 1-Isopropyl-6- (6- (4-isopropylpiperazin-1-yl) pyridin-3-yl) -N- ((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl) methyl) -1H-indazole-4-carboxamide, Ezh1 Inhibitor, Ezh2 Inhibitor IV, HMTase Inhibitor XII, Histone Lysine Methyltransferase XII, Enhancer of Zested Homolog 2 Inhibitor IV)

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