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Bedaquiline

CAT: 0498-bs-82856C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82856C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Bedaquiline is a clinically useful antituberculosis agent that is active (MIC’s 0.030 to 0.120 µg/mL) against multi-drug resistant strains.1 It interferes with mycobacterial energy metabolism via binding to the oligomeric subunit c (AtpE) 2 and subunit 3 of ATP synthase inhibiting ATP production.4 Bedaquiline has recently been found to be an inhibitor (IC50 = 18.7 µM) of the SARS-CoV-2 main protease, 3CLpro.5
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
RT

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