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Icilin

CAT: 0498-bs-82851C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82851C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Icilin is an agonist of cold-sensitive TRP channels with 2.5-fold greater efficacy and 200-fold greater potency than menthol (EC50 = 0.36 µM for CRM1, rat orthologue of TRPM8) .1 Agonist at TRPM8 (EC50 = 0.2 µM) 2 and ANKTM1 (TRPA1) 3. Agonist effects require Ca2+ and are pH dependent.2,4 Icilin induced G1 arrest in PC-3 prostate cancer cells without cell death.5
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C

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CatalogName
255485-01Icilin

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