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Buparlisib

CAT: 0498-bs-82847C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82847C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent pan-Class I PI3-kinase inhibitor (IC50’s: p110α = 52 nM, p110ß = 166 nM, p110δ = 116 nM. P110g = 262 nM) .1,2 It inhibited microtubule dynamics at in vitro concentrations >1µM and doses above 50mg/kg in mice.3 Buparlisib lead to a precipitous drop in DNA synthesis in a mouse model of BRCA1-linked triple-negative breast cancer with less affect in normal tissue.4
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

Alternative Products

CatalogName
HY-70063-01Buparlisib
T16365-01Buparlisib Hydrochloride
C08388-1gBuparlisib (BKM120)
HY-15180-01Buparlisib (Hydrochloride)
HY-70063R-01Buparlisib (Standard)
412131Buparlisib HCl
CS-O-13930Buparlisib-d8

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