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XMU-MP-1

CAT: 0498-bs-82842C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82842C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
XMU-MP-1 is a potent, reversible, and selective inhibitor of the HIPPO pathway kinases MST1 and MST2 (IC50s = 71 nM and 38 nM respectively) .1 It promoted liver repair/regeneration in mice and attenuated acetaminophen-induced liver injury. In a subarachnoid hemorrhage mouse model, XMU-MP-1 alleviated neurological deficits, brain edema, neuroinflammation, and white matter injury.2 XMU-MP-1 was also cardioprotective in mice with transverse aortic constriction3 and against ischemia/reperfusion injury4.
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C

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Alternative Products

CatalogName
C13351-10mM/1mLXMU-MP-1
6482/10XMU MP 1
468878-01XMU-​MP-​1

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