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ERGi-USU

CAT: 0498-bs-82840C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82840C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ERGi-USU selectively inhibits the growth of ERG-positive VCaP prostate cancer cells, COLO320 colon cancer cells, KG-1 and MOLT-4 leukemia cells with minimal effect on ERG-negative cells or normal prostate or endothelial cells (IC50 = 169 nM for cell growth and 315 nM for ERG protein in VCaP cells) . It selectively inhibits the kinase RIOK2 (Kd = 200 nM) causing disruption of ribosomal biogenesis and ribosomal stress.
Conjugation
Unconjugated
Buffer
Red or Orange solid
Storage Conditions
-20°C

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