CGP-37157

CAT: 0498-bs-82832C-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0498-bs-82832C-01Size:10 mg
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Background
Inhibits the mitochondrial Na+-Ca2+ exchanger (NCX) in isolated heart mitochondria, IC50=0.36 μM.1 Does not inhibit the plasmalemmal NCX.2 Also inhibits voltage-gated Ca2+ channels in intact cells and therefore its use in cellular studies must employ adequate controls.3 Prevents sudden death in a Guinea pig model of heart failure.4 Displays pronounced cytoprotective effects in chromaffin cells5 and in neuronal injury models.6 Blood-brain barrier permeant.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
RT

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B6602-10CGP 37157
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A16897-50CGP 37157 50mg
A16897-10mM-DCGP 37157 10mM * 1mL in DMSO
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