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S1RA

CAT: 0498-bs-82821C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82821C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
S1RA (E-52862) is a potent and selective 1 antagonist with weak binding at 2 (IC50’s: 1 = 17nM, 2 = 9300nM) .1,2 S1RA abolished mechanical and thermal hyperalgesia in mice with carrageenan-induced acute inflammation by enhancing the action of endogenous opioid peptides of immune origin in a 1 dependent manner.3 BD1063 potentiated µ-opioid antinociception in mice in a -dependent manner.4 S1RA displayed neuroprotective effects in a mouse model of ischemic stroke.5
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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