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NE-100

CAT: 0498-bs-82820C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0498-bs-82820C-01Size:5 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NE-100 is potent inhibitor of the sigma receptor () with selectivity for sigma-1 (IC50 = 1.5 nM) over sigma-2 (IC50 = 85 nM) .1,2 NE-100 suppressed ischemia-induced neuronal cell death in mice via upregulation of GPR78 through the ATF6 pathway resulting in suppression of ER stress-induced cell death in a sigma 1 independent manner.3
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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