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H-151

CAT: 0498-bs-82808C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82808C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
H-151 is an inhibitor of the signaling molecule STING in mouse and human cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. It reduced systemic cytokine response in mice treated with the STING agonist 10-carboxymethyl-9-acridanone and showed efficacy in Trex-/- mice.
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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