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C-176

CAT:
498-bs-82806C-01
Size:
10 mg
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
C-176 - image 1

C-176

  • Background :

    C-176 is an inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. Treatment of Trex-/- mice with C-176 resulted in a significant reduction in serum levels of Type I Interferons and amelioration of systemic inflammation.

  • Conjugation :

    Unconjugated

  • Buffer :

    Brown or yellow solid

  • Storage Conditions :

    -20°C

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