Products for Research Use Only

UNC6934

CAT: 0498-bs-82799C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82799C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent (IC50 = 104 nM) and selective inhibitor of protein lysine methyltransferase nuclear receptor-binding SET domain-containing 2 (NSD2) . It potently binds to the PWWP1 domain antagonizing interaction with nucleosomal H3K36me2. UNC6934 is selective against 14 other human PWWP domains and 33 methyltransferases. Active in a nanoBRET PPI assay in U2OS cells (IC50 = 1.23 µM) .
Conjugation
Unconjugated
Buffer
Pale yellow solid
Storage Conditions
-20°C

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