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N6022

CAT: 0498-bs-82793C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82793C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
N6022 is a potent and reversible inhibitor of S-nitrosoglutathione reductase (GSNOR) – IC50 = 20 nM1, 8 nM2. It demonstrated significant efficacy in a mouse models of ovalbumin-induced asthma, chronic obstructive pulmonary disease, and irritable bowel syndrome. N6022 was able to attenuate experimental autoimmune encephalomyelitis (an animal model of multiple sclerosis) via selective inhibition of pro-inflammatory CD4+ cells (TH1/TH17) while upregulating anti-inflammatory subsets of CD4+ cells (TH2/Treg) without causing lymphopenia.3
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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B1111-5.1N6022
A13046-10N6022 10mg
A13046-5N6022 5mg
A13046-100N6022 100mg
A13046-50N6022 50mg

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