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Preladenant

CAT: 0498-bs-82792C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82792C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Preladenant is a potent (Ki = 1.1nM) and selective (>1000-fold over other adenosine receptors) adenosine A2A antagonist.1 It has shown efficacy in rodent and primate models of Parkinsons disease without inducing dyskinesias and displays antidepressant effects.1-3 It has been shown that activation of the adenosine A2A receptor blocks the activation of immune cells and increases the number of regulatory T-cells.4-6 Currently in clinical trials as combination therapy with pembrolizumab.7
Conjugation
Unconjugated
Buffer
Beige solid
Storage Conditions
-20°C

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A3735-5Preladenant
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A13504-10Preladenant 10mg
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HY-10889R-01Preladenant (Standard)

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