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TIC10

CAT: 0498-bs-82788C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82788C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TIC10 (1616632-77-9) is novel anti-cancer compound that acts via early-stage integrated stress response activation leading to selective cancer cell death.1-3 TIC10 potently activates mitochondrial caseinolytic protease P (ClpP) causing eIF2-independent induction of ATF4 and Akt/ERK/Foxo3a/DR5/TRAIL-dependent apoptosis.4 Currently in clinical trials.
Conjugation
Unconjugated
Buffer
Pale yellow solid
Storage Conditions
-20°C

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