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IJMJD6

CAT: 0498-bs-82775C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82775C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Inhibitor of the arginine demethylase JMJD6 (IC50 = 220 nM) with selectivity over other JmjC domain-containing proteins.1 Exhibited antiproliferative effects in HeLa (EC50 = 1.49 µM), SMCC7721 (EC50 = 9.37 µM), and MCF7 (EC50 = 9.53 µM) cells.2 Displayed no cytotoxicity towards normal cervical, liver, and breast epithelial cells. iJMJD6 significantly suppressed tumor growth in a HeLa, SMCC7721, MCF7, MDA-MB-231, U87, and HCT116 mouse xenograft models.2
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C

Alternative Products

CatalogName
C01612-100mgIJMJD6
TBI4039-25MGIJMJD6, Arginine demethylase JMJD6 inhibitor

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