PFI-3

• Background:

  PFI-3 (1819363-80-8) is a selective inhibitor of family VIII bromodomains PB1 (5), SMARCA2, and SMARCA4.1 It showed complete selectivity over all non-family VIII bromodomains. PFI-3 blocked adipogenesis in C3H10T1/2 mesenchymal cells at 20µM.Treatment of embryonic stem cells with PFI-3 led to deprivation of stemness and deregulated lineage specificity. Differentiation of trophoblast stem cells in the presence of PFI-3 was enhanced.2 Cell permeable.

• Conjugation:

  Unconjugated

• Buffer:

  Yellow solid

• Storage Conditions:

  -20°C