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GSK2879552

CAT: 0498-bs-82762C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82762C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GSK289552 is potent, selective, and irreversible inhibitor of Lysine Demethylase 1 (LSD1) via covalent modification of the LSD1 cofactor FAD (Ki = 1.7 µM) . It is selective for LSD1 over the closely related LSD2, MAO-A, MAO-B, and the FAD dependent enzymes D-amino acid oxidase and glutathione reductase. Tested against a panel of 165 cancer cell lines, GSK2879552 inhibited the proliferation of 9 small cell lung carcinoma lines and 20 AML cell lines.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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