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A-196

CAT: 0498-bs-82760C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82760C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A-196 (1982372-88-2) is a potent and selective (over 29 other methyltransferases) inhibitor of the protein lysine methyltransferases SUV420H1 (IC50 = 25 nM) and SUV420H2 (IC50 = 144 nM) . It substantially inhibited non-homologous end-joining (NHEJ) -directed DNA repair but not homology-directed repair (HDR) in cells treated with ionizing radiation. A-196 is active in cells and displayed no toxicity in several cell lines.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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