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Elafibranor

CAT: 0498-bs-82719C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82719C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Elafibranor is a dual PPARalpha/delta agonist (EC50 PPARalpha = 10-20 nM; PPARdelta = 100-150 nM) .1 It was able to decrease plasma triglycerides levels1, increase HDL cholesterol levels in human studies1, and improve hepatic and peripheral insulin sensitivity2. Elafibranor’s antidiabetic effects in db/db were without the adverse cardiac effects seen in PPARgamma agonism.3 Elafibranor has also been shown to have therapeutic promise in the treatment of nonalcoholic steatohepatitis (NASH) .4-6
Conjugation
Unconjugated
Buffer
Pale yellow solid
Storage Conditions
-20°C

Alternative Products

CatalogName
BA4428-50Elafibranor
T211707-01Elafibranor sulfoxide

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