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Tigecycline

CAT: 0498-bs-82718C-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0498-bs-82718C-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Tigecycline is a clinically useful antibiotic.1,2 It is a glycylcycline derivative of minocycline that binds to the 30S ribosomal subunit of bacteria blocking the interaction of aminoacyl-tRNA with the ribosome. Tigecycline is active against Gram-positive and -negative bacteria, anaerobic bacteria and drug resistant bacteria such as MRSA, MRSE, and VRE. Tigecycline has also been shown to be selectively toxic to human acute myeloid leukemia cells over normal hematopoietic cells via inhibition of mitochondrial protein translation.3 It has also been found to be effective against other cancers including non-small cell lung cancer4, melanoma5, lymphoma6, and osteosarcoma7.
Conjugation
Unconjugated
Buffer
Orange solid
Storage Conditions
-20°C

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