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Canagliflozin

CAT: 0498-bs-82692C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82692C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), IC50 = 2.2 nM selective over SGLT1, IC50=910 nM.1 Dose dependently increases glucose excretion in healthy subjects.2 Displays beneficial effects in nonalcoholic fatty liver disease (NAFLD) .3 Extends lifespan in male but not female mice.4 Inhibits cancer cell proliferation via inhibition of mitochondrial complex-1 supported respiration.5 Suppresses the growth of pancreatic cancer cells.6
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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CatalogName
A8333-100Canagliflozin

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