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Autophinib

CAT: 0498-bs-82683C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82683C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Inhibits autophagy induced by starvation or rapamycin by inhibiting the lipid kinase VPS34 (IC50=19 nM) .1 Increased autophagy and apoptosis were rescued by autophinib in Per1-overexpressing oral squamous cell carcinoma cells.2 Autophinib has quickly become an important biochemical tool for inhibition of autophagy in a variety of cellular contexts.3-5
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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