Products for Research Use Only

Piericidin A

CAT: 0498-bs-82681C-01Size: 200 µgDry Ice: NoHazardous: No
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CAT#:0498-bs-82681C-01Size:200 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A potent inhibitor of the mitochondrial and bacterial type I NADH-ubiquinone oxidoreductase (complex I) .1 Piericidin A is a ubiquinone analog which binds to the ubiquinone binding site of the enzyme.2 It is an extremely useful tool for exploring the role of complex I in mitochondrial function in both normal and pathophysiology.3-5 Prevents upregulation of GRP78 and induces cell death in glucose-deprived, etoposide-resistant HT-29 cells (IC50=7.7 nM) .6
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C