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NSC59984

CAT: 0498-bs-82648C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82648C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
P53 activator. Restores wild-type p53 signaling and depletes mutant p53 gain of function. Induces mutant p53 protein degradation via MDM2 and ubiquitin-proteasome pathway. Induces p73-dependent cell death in cancer cells without toxicity toward normal cells.1 Inhibition of p53-MDM2 interaction remains a viable strategy for cancer therapeutic development.2,3
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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