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Nilvadipine

CAT: 0498-bs-82637C-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82637C-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A novel DHP L-type Ca2+ channel blocker that also inhibits Syk.1 Blocks Aβ production, APPβ secretion and reduces BACE-1 expression in CHO cells over-expressing Aβ in vitro. Enhances clearance of Aβ across the blood brain barrier in vivo. Reduces brain Aβ levels in a mouse tauopathy model.1 Clinically useful antihypertensive agent.2 Has been shown to prevent cognitive decline in some clinical trials.3 Produces a protective effect on glutamate neurotoxicity in retinal ganglion cells, an effect not shared by other L-type Ca2+ channel blockers such as nifedipine and diltiazem.4
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C

Alternative Products

CatalogName
MBS577425Nilvadipine

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