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Safinamide

CAT: 0498-bs-82611C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82611C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A selective and reversible inhibitor of monoamine oxidase B (MAO-B, IC50=98 nM with greater than 100-fold selectivity over MAO-A.1 Displays anticonvulsant activity2 and protects against kainate-induced seizures and hippocampal neurodegeneration in rat models3. Reduces overactive glutamatergic signaling via use-dependent sodium channel blockade.4 A novel therapeutic for Parkinson’s disease with multiple modes of action.5 Effective as an add-on to dopamine agonist therapy in early Parkinson’s.6
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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CatalogName
A3784-500Safinamide

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