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Z-DEVD-FMK

CAT: 0498-bs-82608CSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82608CSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Z-DEVD-FMK (210344-95-9) is a cell-permeable trimethyl ester form of the irreversible caspase-3 inhibitor DEVD-FMK (fluoromethylketone) with IC50 = 130 nM.1,2 Methyl esters confer cell permeability and are hydrolyzed to the active COOH form via intracellular esterases. Inhibits caspase-3-dependent apoptosis and pyroptosis in a variety of cell lines.3,4 Active in vivo.5
Conjugation
Unconjugated
Buffer
Lyophilized solid
Storage Conditions
-20°C

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A1920-1Z-DEVD-FMK

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