Vildagliptin

• Background:

  A potent inhibitor of dipeptidyl peptidase IV (DPP IV), an enzyme that cleaves glucagon-like peptide 1 (GLP-1) 1. Delaying the degradation of GLP-1 extends the action of insulin and suppressing the release of glucagon which results in reduction in elevated blood glucose levels (hyperglycemia) 2. Clinically useful antidiabetic agent. Ameliorates cognitive deficits in streptozotocin-induced Alzheimers disease model3. Displays protective effects on β-cells by inhibition of ER stress in a mouse model4.

• Conjugation:

  Unconjugated

• Buffer:

  White solid

• Storage Conditions:

  -20°C