Cinnabarinic Acid

• Background:

  A novel endogenous tryptophan metabolite which acts as an aryl hydrocarbon receptor (AHR) agonist1. It drives IL-22 production by stimulating the differentiation of human and mouse T cells producing IL-221. Induces apoptosis in thymocytes2. Activates type 4 metabotropic glutamate receptors3. Counteracts excitotoxic neuronal cell death induced by NMDA in mixed cultures of cortical cells. Displays neuroprotective activity3.

• Conjugation:

  Unconjugated

• Buffer:

  Red solid

• Storage Conditions:

  -20°C