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Kifunensine

CAT: 0498-bs-82600C-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82600C-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Historically isolated from Kitasatosporia kifunensee.1 Inhibitor of class I α-mannosidases which inhibit glycoprotein processing. Inhibits human endoplasmic reticulum α-1,2-mannosidase I and Golgi Class I mannosidases IA, IB and IC with Ki values of 130 and 23 nM respectively.2 Inhibition of endoplasmic reticulum α-mannosidase I activity rescues the human α-sarcoglycan R77C mutation suggesting a new pharmacological approach for limb girdle muscular dystrophy type 2D patients carrying mutations that impair α-sarcoglycan trafficking.3 Improves maturation of misfolded proteins.4
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

Alternative Products

CatalogName
MK10316-01Kifunensine

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