Products for Research Use Only

Nicotinamide

CAT: 0498-bs-82594C-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0498-bs-82594C-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Essential nutrient (amide form of Vitamin B3) that is incorporated into cofactors NADH/NAD+, important for ATP production and other key metabolic functions.1 Transiently inhibits SIRT1/SIRT3 through feedback inhibition (IC50 ~ 50 µM) 2, but is quickly converted to NAD+ in cells3. Also inhibits certain kinases (e.g. ROCK and CK1), making it a regulator of hPSC pluripotency, survival, and differentiation.4 Inhibits differentiation and enhances functionality of hematopoietic stem/progenitor cells (HSPCs) .5
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
RT

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