Thiamet-G

CAT: 0498-bs-82589C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0498-bs-82589C-01Size:5 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent, selective inhibitor of O-GlcNAcase (Ki = 21 nM for human O-GlcNAcase) . Increases levels of O-GlcNAc-modified proteins in cellular assays and in vivo. Suppresses phosphorylation of tau protein in rat cortex and hippocampus.1 Stabilizes tau against aggregation and slows neurodegeneration.2 Prevents cognitive decline and amyloid plaque formation in bigenic tau/APP mutant mice.3 Active in vivo and blood brain barrier permeable.
Conjugation
Unconjugated
Buffer
Pale yellow solid
Storage Conditions
-20°C

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