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Riluzole

CAT: 0498-bs-82586C-01Size: 20 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82586C-01Size:20 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Riluzole is a clinically useful drug for the treatment of amyotrophic lateral sclerosis (ALS) .1 Riluzole inhibits glutamate release via inactivation of voltage-dependent ion channels, effects expression and signal transduction of glutamate receptors, and facilitates glutamate uptake.2,3,4 It has also been investigated as a treatment for depression and anxiety.5 Riluzole induced apoptosis in mGluR1-expressing melanoma cells6, inhibited cell proliferation in a U87MG glioblastoma model via blockage of glutamate release7, and inhibited the growth of brain tumor stem-like cells via downregulation of GLUT3.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
RT

Alternative Products

CatalogName
TRC-R510000-100MGRiluzole

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