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Reserpine

CAT: 0498-bs-82559CSize: 1 gDry Ice: NoHazardous: No
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CAT#:0498-bs-82559CSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Indole alkaloid isolated from Rauwolfia serpentina which acts as a potent antihypertensive agent. Irreversibly inhibits both isoforms of vesicular monoamine transporter VMAT1 and 2, Ki=34 and 12 nM, respectively.1,2 May be used to pharmacologically deplete monoamines in various animal models.3 Inhibits the multidrug resistance protein P-glycoprotein, IC50=0.5 mM.3 Reserpine-induced hypokinesia is considered a useful animal model of Parkinson’s disease.5
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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