Products for Research Use Only

2'-Deoxy-5-fluorocytidine

CAT: 0498-bs-82557C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82557C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A DNA methyltransferase inhibitor currently in clinical trials for breast cancer and other solid tumors1. Like 5’-Azacytidine and decitabine, 2’-Deoxy-5-fluorocytidine is a pyrimidine analog that integrates into chromatin to inhibit DNA methylation2. It blocks proliferation in colon cancer-derived HCT116 cells by activating DNA response pathways3. It inhibits various strains of pathogenic avian influenza viruses in vitro and in vivo4.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C