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Swainsonine

CAT: 0498-bs-82553C-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82553C-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A naturally occurring alkaloidal toxin found in locoweed. Inhibits the biosynthesis of complex glycoproteins by inhibition of Golgi mannosidase II (IC50 = 0.2 μM) .1 Inhibits growth and potentiates the cytotoxic effect of taxol in hepatocellular carcinoma in vivo.2 Induces apoptosis in a variety of cell types including cerebral cortical neurons.3 Impairs adult neurogenesis and spatial learning and memory.4 Abrogation of complex glycosylation by swainsonine results in strain-and cell-specific inhibition of prion replication.5 Induces lysosomal storage disease in farm animals.6
Conjugation
Unconjugated
Buffer
White or off-white solid
Storage Conditions
-20°C

Alternative Products

CatalogName
sc-201362DSwainsonine

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