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Migalastat

CAT: 0498-bs-82542C-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82542C-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Migalastat is a potent, selective, and orally available inhibitor of α-galactosidase A (IC50= 40 nM) .1 It binds to mutant misfolded α-GalA shifting the folding behavior toward functional active conformation (pharmacological chaperone activity) followed by trafficking to the lysosomes.2 Migalastat is active broadly across species from Drosophila3 to human4. Clinically useful agent for Fabry disease.5
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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