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Monastrol

CAT: 0498-bs-82541C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82541C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent, cell-permeable, small molecule inhibitor of mitosis. Monastrol-arrested cells are characterized by monopolar spindles.1 Does not affect other motor proteins or tubulin. Specifically inhibits the mitotic molecular motor kinesin Eg5, a motor protein required for spindle formation (IC50 = 14 μM) .2 Mimics the effect of amyloid β on long term potentiation in a cellular model of learning and memory.3 Enhances regeneration of adult axons.4
Conjugation
Unconjugated
Buffer
Beige solid
Storage Conditions
-20°C

Alternative Products

CatalogName
HY-101071A-01Monastrol

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