Antimycin A

• Background :

  Mitochondrial electron transport inhibitor at complex III. Induces apoptosis in various cell lines.1 Antimycin A may be used to generate cellular models of degenerative disorders by blocking the mitochondrial electron transport chain, disrupting energy metabolism, and elevating ROS levels.2-4 Induces canonical PINK1-Parkin-dependent mitophagy in Parkin overexpressing cells upon cotreatment with oligomycin.5

• Conjugation :

  Unconjugated

• Buffer :

  White solid

• Storage Conditions :

  -20°C