Cilostamide

• Background :

  Selective inhibitor of phosphodiesterase-3 (PDE3) . Displays limited selectivity for PDE3A versus PDE3B (IC50 = 27 and 50 nM) 1,2. Blocks PKB/Akt signaling pathway downstream via inhibition of Akt-activated PDE3B3. Reverses the effect of leptin on food intake and body weight4.

• Conjugation :

  Unconjugated

• Buffer :

  White solid

• Storage Conditions :

  RT