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Stattic

CAT: 0498-bs-82513C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82513C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
STAT3 inhibitor. Inhibits binding of tyrosine-phosphorylated peptides to STAT3 SH2 domain and inhibiting STAT3 activation, dimerization and nuclear translocation1. Displays selectivity over STAT1, STAT5, c-Myc/Max, Jun/Jun and Lck. Induces apoptosis in STAT3-dependent cancer cell lines. Alkyates four cysteine residues on STAT32. Exhibits potent antitumor activity3. Protects against angiotensin II-induced vascular dysfunction and hypertension4. An extremely useful tool to probe involvement of STAT3 in cellular signaling.
Conjugation
Unconjugated
Buffer
Light yellow solid
Storage Conditions
-20°C

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CatalogName
A2224-25Stattic

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