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CD50 Antibody

CAT: 0013-GTR17857370Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR17857370Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse monoclonal antibody to CD50 which is also known as ICAM-3, is belongs to the immunoglobulin superfamily, binds the leukocyte integrins LFA-1 and alphad/beta2. ICAM-3 is expressed on leukocytes and epidermal Langerhans cells. It can play a role in developing functionally mature T lymphocytes and its expression increases during the maturation process of T lymphocytes.
Product Name Alternative
ICAM-3, ICAM-R
UniProt
P32942
Reactivity
Human
Immunogen
Leukocytes of a patient suffering from LGL-type leukemia.
Target
CD50
Clonality
Monoclonal
Clone
MEM-04
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Purified by protein-A affinity chromatography.
Concentration
1 mg/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Functional application: The antibody MEM-04 blocks DC-SIGN (CD209) binding to ICAM-3 (epitope in D1) . Flow cytometry: Recommended dilution: 1-4 μg/ml. Immunohistochemistry (paraffin sections) : Recommended dilution: 10 μg/ml; positive tissue: tonsil.
Tested Applications
FA, FC, IHC-P
Preservative
Phosphate buffered saline (PBS), pH 7.4
Isotype
Mouse IgG2b kappa
Entrez
3385

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